On Vogue’s The Run-Through podcast, host Chloé Malle told Dakota Johnson about a cosmetic trend using cadaver fat for injections, calling it more organic and saying she wanted a reporter to dig into it. Johnson’s take: “I think it’s like recycling. I’m sort of into it.”

Malle floated the idea while the two discussed strange LA procedures, saying Vogue’s beauty editor was looking into it and that the fat could go in the forehead, under the eyes, or into breast implants. Johnson, 36, ran with the mental image, picturing two gurneys with a corpse on one and syringes moving the tissue over to a patient. “Like somebody’s dead body thigh is going in your face?” she asked. Malle compared it to a Celine Song movie, and Johnson landed on “It’s just creepy enough.”

The product does exist. It’s called alloClae, sterilized donor fat injected in-office without liposuction or general anesthesia, and Tiger Aesthetics says more than 2,000 patients have been treated since May 2025, with demand tied to GLP-1 weight loss.

Malle described it as about to be FDA approved, but that isn’t how it’s regulated. alloClae is already sold in the US as a 361 Human Cell and Tissue Product, not a drug or device with FDA premarket approval, and when Allure asked, an FDA representative said the available information wasn’t enough to determine how it’s regulated. Donors also go through screening and disease testing, contrary to Johnson’s guess that testing isn’t required. New York has denied Tiger a tissue license and accused the company of shipping product around the state’s rules.
The episode, tied to Johnson’s October Vogue cover ahead of Verity out October 2, went up September 25.
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